DefenAge 8-in-1 BioSerum

2 SoldOnly 2 left in stock


Size: 1.5 oz. and 1.0 oz.

The 8-in-1 BioSerum is DefenAge’s iconic bestseller. The remarkably smart formula seems to understand your skin’s needs better than your own DNA. Designed to activate, orchestrate and energize, this biologically advanced anti-aging cream-like serum concentrate provides an unprecedented concentration of defensin molecules contained in the Age-Repair Defensin® Complex. Dermatologists and aesthetic professionals name defensins as a perfect retinol alternative and the 8-in-1 BioSerum as a retinol serum replacement. The best part? Results are equal to 8 separate serums. Apply with the 24/7 Barrier Balance Cream to create smoother, younger looking skin. Patent-pending technology. Get the best skin ever today!


  • Rejuvenates smoothness. Improves overall visible skin health and quality.
  •  Minimizes the look of fine lines, wrinkles, pores, and skin pigmentation and discolorations.
  •  Promotes radiance and revives the skin’s natural moisture for an ultimate glow.
  •  Brightens the overall skin tone and clarity and enhances skin luminosity.
  •  Renews the feeling of skin firmness, elasticity, and texture.
  •  Helps improve the appearance of skin redness.
  •  Promotes the skin barrier and immunity.
  • Advanced targeted cosmetic treatment with an established and validated science. A unique mechanism of action.
  •   Contains 5 times more defensin-molecules than any other formulas.
  •  Light-weight application; “you don’t feel it when you’re wearing it”.
  •  Effective and safe for the entire face, including the delicate skin around the eyes and lips, and the neck and décolleté. High performing on the crepey thin skin on the neck and arms.
  •  Fast acting anti-aging – first results are seen within a few weeks.
  •  Perfect as a daily skincare product for both men and women.
  •  Effective for both early and late stages of skin aging, including people above 70.
  •   Non-irritating and gentle on sensitive skin overall, and over retinols.
  •  Tolerated by all skin types. Good for rosacea and melasma patients, can be combined with other treatments for rosacea patients.
  •  Highly effective for pre- and post- aesthetic procedures to achieve the optimal outcomes, including micro needling and fractional and resurfacing/ablative laser treatments. Primes the skin to a quick and robust response. Optimizes healing and minimizes the risk of acne break-outs post-procedure.
  •   Effective to prep the skin and enhance filler results, recommended to use 4-6 weeks before a filler procedure.
  • DefenAge’s most “likable” product with the most impressive consumer feedback.


Daily: AM | PM

  • Place 1 pump of 8-in-1 BioSerum (bio serum) onto fingertips. Lightly massage with fingertips first around eyes, then over entire face. Use a second pump on neck and décolleté. Follow with sunscreen.

Suitable for all skin types.

The 8-in-1 BioSerum is ophthalmologist and dermatologist tested safe for contact lens wearers. Clinically proven effective. The 8-in-1 BioSerum and its key defensin-based ingredient have been tested in 7 clinical studies.


Age-Repair Defensins® | 5X  | DefenAge’s Exclusive

promotes new skin | anti-aging on a global scale | retinol alternative.

Defensins are natural molecules. They signal our body to create new skin by activating the dormant reserves of “fresh” and young cells. DefenAge contains an identical copy of human defensins made via biosynthesis; defensins are exclusive to DefenAge.



hydration | firmness & elasticity | brightening

Niacinamide soothes, revives the skin’s natural moisture barrier, renews the feel of skin firmness and elasticity, and brightens overall skin tone.


Hyaluronic Acid | Low Molecular Weight

| hydration|

Promotes hydration and improves texture for remarkably smooth and even skin.


Sea Whip

| skin calming & soothing |

Keeps skin calm. Strongest, fastest, most effective soothing ingredient from the sea.


Fine Blends of Natural Antioxidants, Enzymes and Hydrating Technologies

antioxidants | hydration | soothing

Our “know-how”-protected, advanced and powerful blends of antioxidants and enzymes address environmental cell damage and defend against free radicals. They brighten, clarify and energize the skin for a revitalized radiance and luminosity.


This product does not contain retinol and should not be considered as a retinol serum.

By size

1.0 oz., 1.5 oz., Pro 1.5 oz.

Start typing and press Enter to search

Shopping Cart

No products in the cart.

Translate »